Deadline: 2025-01-17
External link: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1572&ProjectId=145441&DepartmentId=18958&MediaId=5&SkipAdvertisement=False
Type: Other
Computational scientist for new optical pooled screening infrastructure at the Danish Cancer Institute
Do you want to be part of a state-of-the-art core facility helping researchers understand the genetic underpinnings of complex biological phenomena? The Danish Cancer Institute (DCI) is seeking a highly motivated and experienced computational scientist to support a new open-access infrastructure for microscopy-based pooled CRISPR screening using in situ sequencing. The ideal candidate will have a scientific background in and experience with managing workflows for analyzing biological imaging and CRISPR screening data. The responsibility of the computational scientist is to establish and maintain the computational framework for the infrastructure and provide computational support for users of the infrastructure.
About us
DCI is committed to leading the way in cancer research, focusing on innovative excellence in technology innovation and application. As an integral part of the Danish Cancer Society, we are working to reduce cancer risks, advance early diagnostics, develop novel therapeutic solutions, and improve patients’ lives. We function as a cross-collaborative international cancer research institute with an interdisciplinary and translational agenda, based on excellent research within basic biology and epidemiology. DCI features 23 research groups and a range of core facilities.
About the position
DCI will establish a new open access infrastructure for optical pooled screening (OPS), a state-of-the-art technology for coupling genetic perturbations using CRISPR technologies with visual microscopy-based readouts. The infrastructure will enable researchers across Denmark to perform OPS screens by supporting both the experimental and computational parts of the pipeline. The computational scientist will engage with researchers on their specific projects and provide dedicated support in developing computational analysis tools and pipelines required for performing and analyzing individual OPS screens. Furthermore, the computational scientist will be responsible for establishing the computational infrastructure including data storage and handling.
Start: April 1st, 2025, or after agreement