The Sørensen group at BRIC has one open postdoc position for highly motivated researchers with a desire to investigate molecular mechanisms underlying cancer development and therapy responses.

The goals of the current projects are to understand how familial breast cancers arise as well as identifying weaknesses within malignant cells that can be exploited in the clinic to manage cancer (see the following recent publications, pubmed IDs: 27515922; 27323328; 27113759; 26805514; 25953507). Our group consists of ten dedicated researchers, and we have excellent research facilities in modern laboratories. More information on the Sørensen group onhttp://www.bric.ku.dk/research/Sorensen_Group/

The project aims to unravel new factors in DNA damage checkpoint control with focus on the S and G2 phase cell cycle checkpoints. The checkpoints are partly disabled in cancers, and their complete ablation is a promising anti-cancer approach. We have identified new checkpoint factors operating in response to ionizing radiation, and we will now unravel the functional pathways and molecular mechanisms. The experimental focus will be on biochemical and cell biological approaches, including CRISPR-Cas9 modified cell models.

Application deadline: March 14, 2018.

Start: Preferably May 2018 or after agreement

Duration: 2.5 years

We expect you to be a highly motivated and highly ambitious scientist with the following qualifications:

• A PhD in Medicine or Life Sciences with focus on cancer biology, cancer genetics, biochemistry or similar

• The successful applicant has knowledge in generating and working with CRISPR-Cas9 cell lines as well as documented experimental experience in cell biology, molecular biology, and biochemistry. Experience in advanced fluorescent microscopy techniques and image analysis is important.

• Additional Post doctoral experience up to 3 years would be preferred

• A desire to make a difference through highly dedicated research

• Experimental expertise and substantial knowledge about genome maintenance pathways

• Excellent English skills written and spoken

The employment is within the Sørensen group at BRIC, University of Copenhagen. For further information regarding the positions, please contact Associate Professor Claus Storgaard Sørensen on e-mail: claus.storgaard@bric.ku.dk

BRIC is located in the Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. The Sørensen team has weekly journal clubs and data clubs. BRIC runs seminars with invited speakers, a young researchers club ASAP and our own PhD programme, MoMeD and our own Postdoc Career Programme. Please read more about the Sørensen research group and BRIC onhttp://www.bric.ku.dk/

Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts at 33,224 DKK/ca. 4,429 Euro plus pension. Depending on qualifications, a higher salary may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

Your application must be submitted electronically by clicking ‘Apply now’ below or via BRIC’s website on http://www.bric.ku.dk/jobs/ . The application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page). Indicate preference for project 1, 2, or both.

2. CV incl. education, work/research experience, language skills and other skills relevant for the position.

3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.

4. List of publications.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the above-mentioned requirements.