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High-Accuracy CLEM: Applications at Room Temperature and in cryo

April 7, 2019 - April 14, 2019

Registration is not yet open for this event. If you are interested in receiving more information please register your interest.

Course Overview

This course will teach theory and practice for high-accuracy correlative light and electron microscopy. Students will learn high-accuracy CLEM on resin embedded samples using SEM approaches (Peddie et al. 2014) as well as using TEM according to the procedures developed in the Briggs group at EMBL (Kukulski et al. 2011). The course will also cover the extension of this approach to cryo-EM specimens (Schorb and Briggs 2014), and more recently developed equipment and work flows for cryo-CLEM.

Audience

People with experience in EM who want to further develop their skills in high-accuracy correlated microscopy.

Modules/Resources

The course will combine lectures and hands-on practical work covering all steps in the work flow: sample preparation, microscopy, and image registration/analysis.

Learning Outcomes

Getting hands-on experience of the CLEM methods and tips from the people who developed the methods.

Venue

EMBL Heidelberg, Germany
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